Shorten them quite a bit, bundle them together and put them through some tubing maybe?
I've tried tubing, It worked until I had to rearrange the station. before the rear speakers were tubed until they split for wall mounting. However re-adjusting them when i needed to change rooms was a pain. I currently do have my Mouse and keyboard tubed together to keep the desk nicer.
You could try a cable corral or maybe some Velcro ties? If your desk has the ability for holes to be drilled you could try some routing ports